[Home]HippocampalRhythms

NeuroWiki | RecentChanges | Index | Preferences | Login

Oscillations observed in the hippocampus are:


Theta

4-10 Hz (especially 5 Hz (200 ms)).


Gamma

20-80 Hz (especially 40 Hz (25 ms)).

According to [Draguhn et al], the prevailing view in 1998 was that gamma oscillations are for synchronizing information transmission related to a given object. For example, when thinking about a lemon, information burts corresponding to "round" and "yellow" might fire in synch at 40 Hz. If multiple objects are under consideration, they can be kept separate by spacing them at different phases.

However, perhaps a better supported view is that the theta rhythm is the point of reference for phase. In this view, each 40 Hz cycle represents one "clock tick", and synchronized events can fire anywhere within the same 40 Hz cycle. The "phase" then refers to which 40 Hz cycle is chosen within the 5 Hz theta cycle (apparently, there are about 7 different 40 Hz cycles nested within each 5 Hz cycle (yeah, I know those numbers don't add up, but that's what the following article says)). Evidence for this view is cited in the forth paragraph of [Lisman's 1998 Nature article].


200 Hz

Collective 200 Hz volleys are observed in the hippocampus during the sharp waves.

They occur during rest or sleep. They are spacially coherent up to 5 mm.

There is evidence that the 200 Hz synchronization is mediated through gap junctions (see [Jefferys' web page] or the [Draguhn et al] paper).


Theories

One theory is that memories are first temporarily stored in the hippocampal CA3 region during exploratory behavior and the theta rhythm; then, later on, during rest or sleep, the 200 Hz rhythm facilitates more permanent learning ([Bibbig and Wennekers]).


References

Draguhn, A., Traub, R.D., Schmitz, D. and Jefferys, J.G.R., [Electrical coupling underlies high-frequency oscillations in the hippocampus in vitro], Nature, 394 (July 9, 1998) 189-192.

Lisman, John. [What makes the brain's tickers tock]. Nature 394, 132 - 133 (July 9, 1998).


CategoryOscillation

CategoryMemory

CategoryLimbic


NeuroWiki | RecentChanges | Index | Preferences | Login
Edit text of this page | View other revisions
Last edited February 8, 2003 10:00 (diff)
Search: