The Natural Science Building, Home of the Hedrick Lab

The Hedrick Lab, October 2005

SELECTED RECENT PUBLICATIONS

Dejean, A. S., Deisner, D. R., Kerdiles, Y. M., Babour, A., Arden, K., Castrillon, D. H., DePinho, R. A., Hedrick, S. M. (2009) Foxo3 controls the magnitude of T cell immune responses by modulating dendritic cell function. Nat Immunol. 10(5):457-8. Full Article

Kerdiles, Y. M., Beisner, D. R., Tinoco, R., Dejean, A. S., Castrillon, D. H., DePinho, R. A., Hedrick, S. M. (2009) Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor. Nature Immunology. 10(2): 176-84. Epub 2009 Jan 11. Full Article

D'Souza, W. N., Chang, C. F., Fischer, A. M., Li, M., and Hedrick, S. M. (2008). The Erk2 MAPK regulates CD8 T cell proliferation and survival. J Immunol 181, 7617-7629. Full Article

McGargill, M. A., Choy, C., Wen, B. G., and Hedrick, S. M. (2008). Drak2 regulates the survival of activated T cells and is required for organ-specific autoimmune disease. J Immunol 181, 7593-7605. Full Article

Ch'en, I. L., Beisner, D. R., Degterev, A., Lynch, C., Yuan, J., Hoffmann, A., and Hedrick, S. M. (2008). Antigen-mediated T cell expansion regulated by parallel pathways of death. Proc Natl Acad Sci U S A 105, 17463-17468. Full Article.

Degterev, A., Hitomi, J., Germscheid, M., Ch'en, I. L., Korkina, O., Teng, X., Abbott, D., Cuny, G. D., Yuan, C., Wagner, G., Hedrick, S. M., Gerber, S. A., Lugovskoy, A., and Yuan, J. (2008). Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat Chem Biol 4, 313-321. Full Article

Allen, J. J., Li, M., Brinkworth, C. S., Paulson, J. L., Wang, D., Hubner, A., Chou, W. H., Davis, R. J., Burlingame, A. L., Messing, R. O., Katayama, C. D., Hedrick, S. M., and Shokat, K. M. (2007). A semisynthetic epitope for kinase substrates. Nat Methods 4, 511-516. Full Article.

Peter, M. E., Budd, R. C., Desbarats, J., Hedrick, S. M., Hueber, A. O., Newell, M. K., Owen, L. B., Pope, R. M., Tschopp, J., Wajant, H., Wallach, D., Wiltrout, R. H., Zornig, M., and Lynch, D. H. (2007). The CD95 Receptor: Apoptosis Revisited. Cell 129, 447-450. Full Article

Hedrick, S. M. (2006). The TCR of mice and men. J Immunol 176, 2681-2682. Review-Perspective. Full Article

D'Souza, W. N., and Hedrick, S. M. (2006). Cutting edge: latecomer CD8 T cells are imprinted with a unique differentiation program. J Immunol 177, 777-781. Full Article

Broussard, C., Fleischacker, C., Horai, R., Chetana, M., Venegas, A. M., Sharp, L. L., Hedrick, S. M., Fowlkes, B. J., and Schwartzberg, P. L. (2006). Altered development of CD8+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk. Immunity 25, 93-104. Full Article

Fischer, A. M., Katayama, C. D., Pages, G., Pouyssegur, J., and Hedrick, S. M. (2005). The role of erk1 and erk2 in multiple stages of T cell development. Immunity 23, 431-443. Full Article

Hedrick SM, Cohen DI, Nielsen EA, Davis MM. Pillars article[A.Weiss]: Isolation of cDNA clones encoding T cell-specific membrane-associated proteins. [Nature, 1984, 308: 149-153] J Immunol. 2005 Sep 1;175(5):2771-5 Full Article

Catlett, I., and Hedrick, S. M. Suppressor of Cytokine Signaling 1 is required for differentiation of CD4 T Cells (2005). Nat Immunology, 6:715-21 Full Article

Hedrick, S. M. The acquired immune system: a view from beneath. (2004) Immunity, 21:607-615 Full Article